Calcium gluconate injections 10 percent. Calcium gluconate (injections) - use, indications for use, contraindications. Indications for the use of calcium gluconate-Vial injections and its other types
Calcium gluconate is a fairly well-known drug that replenishes the body with this substance. Available in three dosage forms: in the form of regular and chewable tablets and a solution for injection. The sterile solution for injections is poured into glass ampoules with a volume of 1 to 10 ml. One package can contain 10 ampoules.
The main active ingredient of this product is calcium gluconate. Various ingredients are used as excipients, which vary depending on the dosage form. In the injection solution they are water and calcium sucrose. In this form of the medicinal composition there are 95.5 mg per 1 milliliter of the drug.
What is calcium gluconate and its role in the body
This is a chemical compound that is a calcium salt of gluconic acid. In medical practice it is used as a mineral supplement to replenish calcium reserves in the body.
The drug has a large number of pharmacological effects, among which the main ones are anti-inflammatory, antiallergic, hemostatic and detoxification of the body. Helps maintain optimal concentration of the substance in the body and is one of the constituent elements for the transmission of nerve impulses. Due to it, muscle fibers contract, including in the heart.
In addition, it leads to the restoration of reduced blood clotting and reduces capillary permeability. It is one of the necessary components for maintaining bone density.
When using injections, a rapid onset of effect is observed. This is explained by the lack of metabolic stages necessary to ensure the active form. Immediately after entering the blood, the active substance is ready to perform its functions.
The half-life from the blood is considered to be up to 7 hours from the moment the substance enters the body. Excretion is carried out through the urinary system with urine.
Ca gluconate is able to pass through the placenta, enter milk and be transmitted to the baby during breastfeeding.
Why are they prescribed as injections and are there any contraindications?
Calcium gluconate in parenteral form is necessary to eliminate many pathological conditions. In particular, those that lead to a decrease in the level of this trace element in biological fluids (mainly blood) and ensure the physiological processes occurring with its participation.
The main indications for the use of injections and tablets are:
- The development of hypocalcemia, which occurs due to various reasons.
- Identification of insufficient functioning of the parathyroid glands, which leads to the fact that the microelement is excreted from the body in larger quantities.
- Development of parenchymal hepatitis, the influence of toxic substances on its cells.
- Inflammatory processes in the urinary system, leading to increased excretion of the element in the urine.
- Use as a component of complex therapy in the development of an inflammatory process of various origins, which results in pronounced exudation of plasma outside the vascular bed.
- As part of complex therapy with antihistamines for allergic diseases: itchy,.
- One of the nonspecific therapy options for stopping bleeding of various origins, among which the most common are gastrointestinal, pulmonary, nasal, uterine, etc.
- Poisoning with substances containing magnesium salt, oxalic acid, oxalates and other substances that interact with the active substance, thereby not showing their toxic effects.
When prescribing the drug, you should carefully read the instructions and exclude possible conditions that act as contraindications for use. Among them the main ones are:
- The presence of hypercalcemia, i.e. a condition associated with increased levels of calcium ions in the blood.
- Enhanced excretion of microelements by the urinary system.
- The development of dysfunction of the urinary system associated with impaired filtration and concentration. In addition, it can be either acute or chronic renal failure.
- A disorder of the blood coagulation system, in which there is a tendency to develop thrombotic complications or thickening.
- The presence of individual hypersensitivity to a substance or a history of an allergic reaction to medications of these groups.
Instructions for use in the form of injections
The drug, available in ampoules, should be administered parenterally. The instructions for use indicate that it can be administered intramuscularly or intravenously. It is produced in compliance with all sterility conditions. How to inject calcium gluconate: intramuscularly or intravenously is always decided by the doctor.
Before administering the solution, you should carefully read the instructions, in particular, for contraindications. The expiration date and concentration of the active substance, as well as the integrity of the ampoule are checked.
The solution must be administered warmed to body temperature both intramuscularly and intravenously. The optimal temperature is 37 degrees.
The instructions for using the drug in ampoules say that the average therapeutic dose for an adult is considered to be 5 or 10 ml of solution once a day. In some cases, the frequency is reduced to using the medicine once every 2 or 3 days.
The maximum dosage for children is considered to be a volume equal to 5 ml of the drug with a frequency of no more than 1 time in 2 days. This is largely due to the high risk of necrotic changes in muscle tissue. The drug can be taken from birth. Many parents often have a question: is it possible to take calcium gluconate intramuscularly? The answer to this is this: this drug is not used intramuscularly to treat children, as tissue necrosis is possible. This is why calcium gluconate is prescribed intravenously.
The duration of treatment and dosage selection are carried out as planned, depending on the type of pathology and the severity of the condition.
Use during pregnancy and breastfeeding
The use of the medicine during pregnancy and lactation is not prohibited. The dosage remains the same as for an adult. Administration must be done with extreme caution in order to monitor the woman’s condition. If the drug is poorly tolerated, stop using the drug. The injectable form should be used during pregnancy and breastfeeding only when the expected benefit outweighs the risk.
Symptoms of overdose and possible harm to health
Adverse conditions resulting from the administration of a large amount of the drug or non-compliance with the dosage regimen are extremely rare. Especially when using the medicine by injection. But the doctor and the patient should be careful about changes in well-being during therapy with this drug in order to prevent the possible development of side effects or overdose. That is why it is important to know the clinical manifestations of negative effects on the body, among which are:
- Decreased appetite, up to complete refusal to eat with the development of anorexia.
- An increase in the frequency of urination while maintaining a sufficient volume of urine during the act, which can subsequently create a dehydration clinic.
- Violation of the rhythm of heart contractions and changes in frequency towards tachycardia.
- The appearance of nausea and vomiting, which will not bring relief, and diarrhea, which quickly leads to dehydration.
- The presence of irritation in the area of the skin where the drug was administered. This may be swelling, redness, pain. An extremely rare situation is the development of muscle tissue necrosis.
In such cases, subsequent administrations of the drug should be cancelled. If necessary, you should consult a doctor. There is no specific therapy; it is limited to eliminating symptoms. In some cases, infusion therapy with saline has a good effect.
The occurrence of side effects during treatment with this drug is quite common. This is largely due to incorrect dosing regimens, administration errors, or patient hypersensitivity. However, adverse reactions that pose a threat to life are rare.
If severe side effects develop that lead to deterioration of health or exacerbation of various diseases, the drug should be discontinued. No agents are used as antidotes. If necessary, symptomatic therapy is carried out, but, as a rule, with the exception of necrosis, all conditions go away on their own after stopping the administration of the drug.
Drug interactions with other drugs
Calcium gluconate may slow down the absorption of some types of antibiotics, in particular quinolones, tetracyclines, as well as trace elements such as fluoride and iron. In order to prevent such a condition, medications should be administered at a certain interval of at least 3 hours.
When taken with cardiac glycosides, toxicity to the heart muscle may increase. When introduced into therapy together with calcium channel blockers, their effectiveness decreases.
The drug increases the toxic effects of quinidine. And also it should not be used simultaneously with drugs from the group of carbonates, sulfates, salicylates and ethyl alcohol. This is due to the risk of forming an insoluble compound.
Evaluation of the drug by patients and doctors
Calcium injections were prescribed by a gynecologist for exacerbation of endometritis, which occurred with prolonged bleeding. After just 4 injections, the discharge stopped and the pain noticeably decreased. It was recommended to carry out a preventive course during the period of exacerbation.
Valentina 45 years old
I have been using the drug for 6 years together with antihistamines for periods of exacerbation of allergies. Helps quickly eliminate symptoms and has no side effects.
Anna is 20 years old.
Quite often we prescribe calcium gluconate, especially for inflammation and bleeding. The drug is relatively harmless compared to many other drugs, but shows a good effect. Often this drug is prescribed at the onset of allergy season in women with allergies.
Sergey Vladimirov, obstetrician-gynecologist
How to store and how much it costs
It is recommended to store ampoules with the composition under temperature conditions of no less than 5 and no more than 25 degrees for 30 months, i.e. 2.5 years. They must be in cardboard packaging and protected from access by children. Freezing the drug or creating conditions under which there will be sudden temperature changes is not allowed.
As soon as the package is opened, mandatory use of the drug is required. Partial use of the ampoule with the remaining part of the drug in the future is not allowed. After collecting calcium gluconate into the syringe, you must dispose of the ampoule in accordance with all rules for storing medical waste.
The average price of calcium gluconate in ampoules is approximately 100-120 rubles. The drug is sold without a doctor's prescription.
What can be replaced
Among the analogues of Calcium gluconate, in terms of the achieved effect, as well as the determination of the active substance of the drugs, one should highlight Calcium gluconate injections - Vial. It contains calcium gluconate monohydrate, lactic acid, calcium hydroxide and injection water. The monohydrate form of the substance assumes the presence of an attached water molecule in the chemical formula. The price of the drug is about 90 rubles.
If we consider analogues in a different dosage form, then the injections can be replaced with tablets of the same drug.
Physiologically, all processes in the body are carried out thanks to microelements and macroelements. The important ones are sodium, potassium and magnesium.
Calcium gluconate is a salt that is used as an additional source of calcium. This is justified in many disorders because calcium is important for muscle contraction (cardiac and skeletal muscles).
Ca is one of the coagulation factors. Calcium salts form the bone and cartilage matrix and participate in the normal ionic functioning of nerve fibers.
This element performs a plastic function, ensuring cell adhesion during regeneration and tissue formation.
When prescribed, what calcium gluconate injections help with - indications
Hot injections of calcium gluconate - indications for use are as follows.
Allergic diseases
The main pathophysiological reaction in allergies is vasodilation in response to histamine. Histamine, in turn, is released in response to an allergen. When the wall expands, the liquid part of the blood enters the tissue and swelling and itching appear. The medicine reduces the permeability of the vessel wall and, therefore, relieves swelling.
A separate property can be considered that Ca activates the sympathetic system, which produces catecholamines - important hormones for stopping the allergic reaction by normalizing the membranes of mast cells and stopping the release of histamine. Plus, catecholamines reduce the gap between vascular cells.
Calcium gluconate is prescribed together with hormonal and antihistamines to enhance and consolidate the clinical effect.
Decrease in Ca content
A chemical element in an unbound form is not absorbed! This problem was solved by deriving a related formula. In this chemical form, calcium is well absorbed and distributed to important biochemical reactions.
Insufficiency of the coagulation system
The coagulation system is responsible for stopping hemorrhage when the vascular wall is damaged. This is a complex of cascade reactions (that is, the result of one reaction triggers the next reaction, and so on). As a result, a clot (thrombus) is formed, clogging the damaged lumen of the vessel. Ca plays one of the main roles in the formation of this clot, and calcium gluconate injections are used to enhance the functioning of the coagulation system.
Increased capacity of the vascular wall
The drug causes a contraction of the vascular glucocorticoid layer, which reduces the gap between cells and reduces the ability to pass allergens and other components.
Inflammatory diseases of the liver and kidneys
Inflammatory changes are accompanied by the same vasodilation reaction against which the drug is used.
The drug also replenishes the lack of calcium in the body and promotes the normal functioning of biochemically important processes. And this speeds up recovery.
During pregnancy, the medicine eliminates many typical symptoms and serves as an active supplement.
In case of poisoning with various ions. For example, Mg or acid salts.
Calcium gluconate in ampoules - instructions for use
The product is produced both in tablet form and in solution form.
The medical solution for injection is poured into ampoules of 5 ml. One milliliter contains 0.1 mg of active substance.
When used parenterally (in tablet form), side effects such as difficulty with bowel movements and abdominal pain may occur.
Injection methods of administering the drug have a more pronounced and rapid therapeutic effect. And side effects are less pronounced.
Intravenous injections are given only on an outpatient basis. This is necessary to maintain sterility and correct administration technique.
First, prepare the required dosage of the medicine. The dose for an adult is 5-10 ml per day. They prepare it over a sterile table, looking at the year of manufacture and making sure that the panacea is suitable. The liquid is warmed to body temperature, diluted with sodium chloride and drawn into a sterile syringe.
Attention! The container should not contain particles of the alcohol solution, since the medicine, when interacting with it, forms a precipitate that is unsuitable for use!
Ca gluconate is given intravenously slowly, over 2-3 minutes. During this, fever, discomfort in the mouth, sweating, nausea and weak stool may occur. But these effects wear off pretty quickly.
Calcium gluconate - instructions for use intramuscular injections
Intramuscular administration is more accessible for home use. The medicine is also taken over the sterile area with treated gloved hands. Use 1 ampoule, that is, 5 ml of the drug. Enter slowly.
After completing the injection, treat with alcohol cotton wool and perform several massage movements.
Hot injections of calcium gluconate and calcium chloride (chloride) - the difference
The substance can be associated not only with gluconic acid, but also with chlorine. This compound is called calcium chloride, and according to its pharmacological properties it is considered an analogue of calcium gluconate.
Unlike its analogue, calcium chloride cannot be taken intramuscularly or subcutaneously. It should be diluted intravenously with a large amount of isotonic solution (about 150-200 ml) and administered more slowly. Subcutaneous and intramuscular administration causes tissue necrosis, which is a serious side effect.
In terms of clinical effectiveness, calcium chloride has a better antiallergic and anti-inflammatory effect.
Contraindications to the use of solution in ampoules
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Possible side effects
When using the solution in ampoules intravenously, the following are possible: fever starting in the mouth (spreading throughout the body), dizziness, nausea. Symptoms go away on their own within 5 minutes.
When administered intramuscularly, the appearance of infiltrates and necrosis of muscle tissue at the injection site were observed.
Compatibility of Calcium Gluconate with other medications
The use of the medication is unacceptable together with tetracycline antibiotics. In such an active compound, calcium gluconate neutralizes the antibacterial clinical effect.
Not to be used in conjunction with thiazide diuretics. This drug group reduces the filtration of calcium by the kidneys and increases the calcium level in the blood. When drugs are used together, hypercalcemia may occur.
Important! When treating with calcium preparations, it is necessary to exclude from the diet foods containing sulfates, salicylates, and carbonates, since precipitation is formed that negatively affects kidney function.
Alcoholic products and calcium gluconate are absolutely incompatible.
The interaction of calcium gluconate and ethyl alcohol leads to the formation of a precipitate. For this reason, drinking alcohol and simultaneously using an injectable drug is not recommended.
Plus, ethanol leads to increased excretion of Ca salts from the body, which overrides the therapeutic effectiveness.
Let's look at the instructions for using calcium gluconate in injections. In the form of tablets for oral administration, the medicine has been familiar to pharmacy customers for many decades.
A solution for intramuscular and intravenous administration of Calcium gluconate is available in ampoules. The volume of the solution can be 5 or 10 ml, 5, 10 or 20 ampoules in a box with instructions for use.
Manufacturers are different.
Each milliliter of the medicine contains 100 mg of calcium gluconate, 10 ml - 1 g, respectively.
Properties of calcium
Calcium is an essential macronutrient necessary for the normal functioning of our body. He takes an active part in the following processes:
- metabolism;
- muscle contractions;
- secretion of hormones;
- during blood clotting;
- formation of bone tissue.
Deficiency of this element leads to various disruptions in the functioning of systems and organs, as well as the occurrence of diseases. For example, tetany is attacks of muscle cramps that appear when there is a deficiency and disturbance of calcium metabolism in the body.
Calcium gluconate replenishes the body with the necessary amount of macronutrients, has anti-allergic, anti-inflammatory and homeostatic effects. With intravenous administration of the solution, the secretion of norepinephrine by the adrenal glands increases, and some diuretic effect appears.
Indications for use
- hypocalcemia;
- bleeding;
- increased permeability of blood vessels;
- decreased vascular permeability (hemorrhagic vasculitis);
- allergies;
- nephritis;
- parenchymal or toxic hepatitis;
- eclampsia;
- poisoning with magnesium salts and oxalic acid.
Contraindications
- individual intolerance to the drug;
- excess calcium in the body (hypercalcemia);
- hypercalciuria (excretion of large amounts of calcium in the urine);
- increased blood clotting;
- atherosclerosis (vascular disease in which cholesterol is deposited on their walls and plaques form);
Carefully
For urolithiasis. In this case, it is recommended to increase the drinking regime and undergo laboratory determination of calcium in the urine.
Dosing
The solution is administered intravenously or intramuscularly, slowly, warmed to body temperature.
Adults: 5-10 ml of calcium gluconate every day, 1 time or every 2-3 days. Intramuscular administration is not recommended for children. If absolutely necessary, the dosage is 1-5 ml every 2-3 days.
Overdose
The instructions for use do not describe such cases.
Side effect
- nausea and vomiting;
- constipation;
- bradycardia;
- hypercalciuria;
- with intramuscular administration - tissue necrosis.
Interaction with other drugs
- Along with calcium channel blockers, calcium gluconate reduces their effect.
- With verapamil, it reduces its hypotensive effect.
- With cardiac glycosides, the cardiotoxic effect is enhanced.
The drug "Calcium gluconate" belongs to the pharmaceutical group of regulators of calcium-phosphorus metabolism. The product helps to replenish Ca2+ deficiency, which is an important component of impulse nerve transmission and contraction of smooth and skeletal muscles.
The drug is involved in the activity of the myocardium, blood clotting, and bone tissue formation. The drug “Calcium gluconate” is prescribed intravenously, intramuscularly and orally.
Purpose
The drug is recommended for pathologies complicated by hypocalcemia, increased permeability of cell membranes (including blood vessels), and disorders of impulse transmission in muscle tissue. Indications include hypoparathyroidism (osteoporosis, latent tetany), vitamin D metabolism disorders - rickets (osteomalacia, spasmophilia), hyperphosphatemia. The drug "Calcium gluconate" (intravenous) is recommended for increased need for Ca2+ during pregnancy, increased growth and development of the body, and during lactation. The drug is indicated for insufficient calcium intake from food, disorders of its metabolism (including postmenopause).
The drug is prescribed for chronic diarrhea, prolonged stay in a supine position, secondary hypocalcemia due to long-term use of diuretic drugs, glucocorticosteroids, and antiepileptic drugs. The drug “Calcium gluconate” (intravenously) is recommended for poisoning with fluoric and oxalic acids, Ma2+.
Contraindications
The drug is not prescribed for hypercalcemia, intolerance, nephrourolithiasis, severe hypercalciuria, when taken simultaneously. Contraindications include sarcoidosis, age up to 3 years. Dose adjustment may be required for dehydration, electrolyte disturbances, malabsorption syndrome, diarrhea. Caution should be exercised in case of a history of calcium nephrourolithiasis, slight hypercalcemia, hypercoagulation, and widespread atherosclerosis.
Dosage regimen
The drug "Calcium gluconate" is administered intravenously slowly. For children, the infusion is carried out within 2-3 minutes. The dosage is set according to age, from 1 to 5 milliliters of a ten percent solution every 2 or 3 days. Adults are prescribed 5-10 ml every day, every other day or two. The application regimen is established in accordance with the course of the pathology. Before administering Calcium Gluconate intravenously, the solution should be warmed to body temperature.
Adverse reactions
When using the drug "Calcium gluconate" intravenously, nausea, bradycardia, diarrhea, and vomiting occur. A feeling of heat and burning in the mouth is likely. With rapid administration, blood pressure decreases, arrhythmia develops, cardiac arrest and fainting are likely.
Additional Information
In case of overdose, hypercalcemia occurs. As therapy, Calcitonin is prescribed parenterally at 5-10 IU/kg per day, diluted in 500 ml NaCl (0.9%). The duration of administration is six hours.
A drug used to normalize tissue metabolism is Calcium gluconate. Instructions for use prescribe taking 500 mg tablets, injections in ampoules for intramuscular and intravenous injections to replenish calcium deficiency in the body.
Release form and composition
The drug is available in the following dosage forms:
- Tablets 500 mg.
- Chewable tablets 500 mg.
- Solution for intravenous and intramuscular administration (injections) in ampoules of 100 mg/ml.
The active substance is calcium gluconate.
pharmachologic effect
Calcium is an essential macronutrient that is involved in the processes of bone tissue formation, transmission of nerve impulses, and blood clotting. This macronutrient is also necessary to maintain normal cardiac activity.
Calcium improves muscle contraction in muscle dystrophy and myasthenia gravis, and also reduces vascular permeability. When administered intravenously, calcium gluconate exhibits a moderate diuretic effect, and also increases the secretion of adrenaline by the adrenal glands and causes stimulation of the sympathetic nervous system.
Indications for use
Why is calcium gluconate prescribed? It is advisable to prescribe injections and tablets for:
- increased need for calcium (pregnancy, breastfeeding, periods of intensive growth in children/adolescents);
- hypoparathyroidism (osteoporosis, latent tetany);
- hyperphosphatemia in patients with chronic renal failure;
- Ca metabolism disorders in the postmenopausal period;
- disorders of vitamin D metabolism (spasmophilia, rickets, osteomalacia);
- conditions that are accompanied by increased calcium excretion (chronic diarrhea, prolonged bed rest; long-term treatment with diuretics, corticosteroids or antiepileptic drugs);
- bone fractures;
- poisoning with oxalic acid, Mg salts, soluble salts of fluoric acid (the advisability of using the product as an antidote is due to the fact that, interacting with these substances, Ca gluconate forms non-toxic Ca oxalate and Ca fluoride);
- insufficient Ca content in the diet.
As an addition to the main treatment, Calcium Gluconate tablets are used as a means of:
- for bleeding of various origins, nutritional dystrophy, bronchial asthma, pulmonary tuberculosis, parenchymal hepatitis, eclampsia, nephritis, toxic liver damage;
- from allergies with itchy dermatoses, febrile syndrome, urticaria, serum sickness, angioedema.
Instructions for use
Calcium gluconate tablets must be crushed before use. Prescribed orally, before meals or 1-1.5 hours after meals (with milk).
Adults - 1-3 g 2-3 times a day (maximum daily dose - 9 g).
Pregnant and nursing mothers - 1-3 g 2-3 times a day (maximum daily dose - 9 g).
For children, the frequency of administration is 2-3 times a day:
- 3-4 years - 1 g (maximum daily dose - 3.0 g);
- 5-6 years - 1-1.5 g (maximum daily dose - 4.5 g);
- 7-9 years - 1.5-2 g (maximum daily dose - 6 g);
- 10-14 years - 2-3 g (maximum daily dose - 9 g).
Intravenously the drug must be administered slowly, just like calcium gluconate injections ( intramuscularly) – they are done for two to three minutes. Adults are administered 5-10 ml of a 10% solution every day, every other day or two days.
For children, calcium gluconate injections are not given intramuscularly (due to the risk of tissue necrosis); the drug is administered only intravenously (slowly or drip) - 1-5 ml of a 10% solution every two to three days. Before administration, the solution must be warmed to normal body temperature.
Contraindications
Calcium gluconate is contraindicated for use if you have the following diseases or disorders:
- severe atherosclerosis;
- hypercalcemia;
- hypercoagulability;
- tendency to thrombosis.
The drug is not used for severe renal failure. In patients with mild renal impairment, as well as a history of urolithiasis or mild hypercalciuria, the drug should be used with caution. In such cases, treatment should be carried out under conditions of regular monitoring of the level of calcium excretion in the urine.
For those patients who have a tendency to form stones in the urine, it is necessary to increase the volume of fluid consumed during treatment with calcium preparations. Children are not recommended to receive intramuscular injections of calcium gluconate.
Side effects
The drug is usually well tolerated, but in some cases the following disorders are possible:
- hypersensitivity reactions;
- impaired renal function (swelling of the lower extremities, frequent urination);
- formation of calcium stones in the intestines (with long-term use of high doses of the drug);
- bradycardia;
- nausea, vomiting, stool disorders (constipation/diarrhea), epigastric pain;
- hypercalciuria, hypercalcemia.
With parenteral administration, nausea, vomiting, bradycardia, diarrhea, a feeling of heat in the mouth and then throughout the body, and changes in the skin may sometimes be observed. These reactions pass quite quickly and do not require special treatment.
With rapid administration of the solution, nausea, increased sweating, vomiting, arterial hypotension, and collapse (in some situations, lethal) may occur. The result of extravasal penetration of the solution can be calcification of soft tissues. When calcium gluconate is administered intramuscularly, local irritation and tissue necrosis are possible. In very rare cases, allergic and anaphylactic reactions have been recorded.
Children, pregnancy and breastfeeding
The dosage of calcium gluconate during pregnancy is determined by your doctor. The maximum amount of the drug per dose for this category of patients does not exceed 500 mg. The frequency of appointments is determined by the attending physician. To avoid the development of side effects during pregnancy, it is very important to strictly follow the drug regimen prescribed by your doctor.
The drug in tablets is not prescribed to children under 3 years of age. The solution for intramuscular injection is not used in childhood.
special instructions
In patients with mild hypercalciuria, decreased glomerular filtration rate, or a history of nephrourolithiasis, treatment should be carried out under the control of the concentration of calcium ions in the urine.
To reduce the risk of developing nephrourolithiasis, drinking plenty of fluids is recommended. Calcium gluconate has similar effects to calcium chloride, but is less irritating.
Drug interactions
The simultaneous use of calcium supplements with calcium channel blockers reduces the pharmacological effect of the latter. When combining oral forms of calcium gluconate and tetracyclines, the absorption of tetracycline drugs is impaired, and therefore their pharmacological effect is reduced.
Cholestyramine reduces the absorption of calcium from the gastrointestinal tract. Quinidine in combination with calcium slows down intraventricular conduction. As a result of this combination of drugs, the toxicity of quinidine increases. With intravenous administration of calcium before or after the use of Verapamil, the hypotensive effect of the drug is reduced.
Parenteral use of calcium supplements is also not recommended during treatment with cardiac glycosides, since this combination of drugs leads to increased cardiotoxic effects.
Analogues of the drug Calcium gluconate
- Calcium pangamate.
- LecT.
- Calcium lactate.
- Glycerophosphate granules.
- CalViv.
- Calcium gluconate-Vial.
- Additive calcium.
- Calcium-Sandoz.
- Hydroxyapatite.
- B. Brown.
Vacation conditions and price
The average cost of calcium gluconate (tablets 500 mg No. 20) in Moscow is 52 rubles. The price of 10 ampoules of 5 ml is 117 rubles. Available without a prescription.